Clark Gregg began his acting career as a founding member and former artistic director of the Atlantic Theater Company in New York. He has acted in many of the company's productions, including Boys' Life at Lincoln Center, Mojo, The Night Heron, Sexual Perversity in Chicago and Happy Hour, written by Ethan Coen. He also appeared in the original Broadway production of A Few Good Men, by Aaron Sorkin.
Gregg moved to Los Angeles in the mid-90s to pursue film and television work, landing roles in films including Mr. Popper's Penguins, Thor, Iron Man and Iron Man 2, 500 Days of Summer, Choke, In Good Company, Spartan, State and Main, Lovely and Amazing, The Human Stain, We Were Soldiers, One Hour Photo and Magnolia. He played the role of Hank/Henrietta in Tod Williams' debut feature, The Adventures of Sebastian Cole, for which he received an Independent Spirit Award nomination. In 2012 he reprised his role as S.H.I.E.L.D. Agent Phil Coulson in Marvel's The Avengers, which broke box-office records.
Gregg has been seen in several films, including Joss Whedon's Much Ado About Nothing, CBS Films' The To Do List, Very Good Girls, with Dakota Fanning, and Jason Reitman's Labor Day, with Kate Winslet and Josh Brolin. On television he has had recurring roles on The West Wing, Sports Night, Will and Grace, Sex and the City and The Shield, and co-starred with Julia Louis-Dreyfus on CBS' The New Adventures of Old Christine.
An experienced screenwriter and director, Gregg's screenwriting debut, What Lies Beneath (Dreamworks), starred Harrison Ford and Michelle Pfeiffer and was directed by Robert Zemeckis. His feature film directing debut, Choke, which he adapted from the novel by Chuck Palahniuk, starred Sam Rockwell and Anjelica Huston, and premiered at the 2008 Sundance Film Festival, where it was awarded a Special Jury Prize for Best Ensemble before being acquired by Fox Searchlight. His second film as writer-director, the dark indie comedy Trust Me, starred Gregg along with Sam Rockwell, Allison Janney, Felicity Huffman, William H. Macy and Amanda Peet. The film premiered at the 2013 Tribeca Film Festival and was released in May 2014.