Natalia Cordova-Buckley was born in Mexico City and raised in Cancun. As a young girl, she developed an immense talent for dance and was accepted into the dance company, "Centro de Arte Siglo XXI." While there, she trained under renowned ballet teacher Fernando Alonso, who is considered the father of Cuban Classical Ballet. At the age of 17, she was accepted to the prestigious North Carolina School of the Arts' drama department, a selective high school program for seniors in fine arts. After graduating from NCSA's high school program, she attended the theatre conservatory at Cal‐Arts in California.
Cordova-Buckley scored her first major leading role in the feature film Ventanas al Mar, opposite Spain's veteran actors Charo López and Fernando Guillén. Her resume as an actress includes Disney's feature film McFarland U.S.A. and the hit A&E series Bates Motel, where she worked opposite Vera Farmiga and Freddie Highmore as their attorney, Julia Ramos.
Cordova-Buckley was offered the role of Elena "Yo-Yo" Rodriguez in season three of Marvel's Agents of S.H.I.E.L.D. and quickly became a fan favorite. She was brought back for season four, and Marvel created the digital series Slingshot, which revolved entirely around her character. Slingshot was the 2017 Webby Award winner for People's Voice Award Drama: Longform or Series and was nominated for a 2017 Emmy for Outstanding Short Form Comedy or Drama Series.
Cordova-Buckley resides in Los Angeles with her husband Brian Buckley, a musician and actor, and their two dogs, Lorca and Bukowski.